Evidence for the exacerbation of lymphedema of geochemical origin, podoconiosis, by onchocerciasis.
Identifieur interne : 006297 ( Main/Exploration ); précédent : 006296; suivant : 006298Evidence for the exacerbation of lymphedema of geochemical origin, podoconiosis, by onchocerciasis.
Auteurs : Fidelis Cho-Ngwa [Cameroun] ; Alfred Ngwa Amambua ; Melvin Anyasi Ambele ; Vincent P K. TitanjiSource :
- Journal of infection and public health [ 1876-035X ] ; 2009.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Animaux, Cameroun (épidémiologie), Environnement, Femelle, Filariose lymphatique (parasitologie), Filariose lymphatique (épidémiologie), Filariose lymphatique (étiologie), Humains, Immunoglobuline G (sang), Jeune adulte, Lymphoedème, Mâle, Onchocerca (isolement et purification), Onchocercose (), Onchocercose (sang), Onchocercose (épidémiologie), Prévalence, Sujet âgé, Test ELISA, Wuchereria bancrofti (isolement et purification), Études transversales.
- MESH :
- isolement et purification : Onchocerca, Wuchereria bancrofti.
- parasitologie : Filariose lymphatique.
- sang : Immunoglobuline G, Onchocercose.
- épidémiologie : Cameroun, Filariose lymphatique, Onchocercose.
- étiologie : Filariose lymphatique.
- Adulte, Adulte d'âge moyen, Animaux, Environnement, Femelle, Humains, Jeune adulte, Lymphoedème, Mâle, Onchocercose, Prévalence, Sujet âgé, Test ELISA, Études transversales.
- Wicri :
- geographic : Cameroun.
English descriptors
- KwdEn :
- Adult, Aged, Animals, Cameroon (epidemiology), Cross-Sectional Studies, Elephantiasis, Filarial (epidemiology), Elephantiasis, Filarial (etiology), Elephantiasis, Filarial (parasitology), Environment, Enzyme-Linked Immunosorbent Assay, Female, Humans, Immunoglobulin G (blood), Lymphedema, Male, Middle Aged, Onchocerca (isolation & purification), Onchocerciasis (blood), Onchocerciasis (complications), Onchocerciasis (epidemiology), Prevalence, Wuchereria bancrofti (isolation & purification), Young Adult.
- MESH :
- chemical , blood : Immunoglobulin G.
- geographic , epidemiology : Cameroon.
- blood : Onchocerciasis.
- complications : Onchocerciasis.
- epidemiology : Elephantiasis, Filarial, Onchocerciasis.
- etiology : Elephantiasis, Filarial.
- isolation & purification : Onchocerca, Wuchereria bancrofti.
- parasitology : Elephantiasis, Filarial.
- Adult, Aged, Animals, Cross-Sectional Studies, Environment, Enzyme-Linked Immunosorbent Assay, Female, Humans, Lymphedema, Male, Middle Aged, Prevalence, Young Adult.
Abstract
The study was conducted to investigate a variation in the distribution of endemic elephantiasis previously determined to be of geochemical origin in three neighbouring and essentially homogenous villages, Bambili, Bambui and Finge of the Bambui Health District of NW Cameroon. A total of 301 subjects were examined for onchocerciasis and lymphatic filariasis in the area using standard procedures. The onchocercal microfilarial prevalence varied from 6.5% in Bambili through 20.4% in Bambui to 60.4% in Finge. The onchocercal serological prevalence based on IgG4 detection followed a similar trend. By contrast, blood microfilariae were absent in the area as verified by use of sensitive techniques. The community prevalence of elephantiasis varied from 1.1% in Bambili to 4.4% in Bambui and 10.4% in Finge. The correlation between the parasitological prevalence of onchocerciasis and the prevalence of lymphedema in the three villages was strong (r=0.99, p<0.05). We confirm that the elephantiasis in the area is of geochemical origin and the results suggest that it is being exacerbated by onchocercal lymphadenitis.
DOI: 10.1016/j.jiph.2009.09.006
PubMed: 20701883
Affiliations:
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A total of 301 subjects were examined for onchocerciasis and lymphatic filariasis in the area using standard procedures. The onchocercal microfilarial prevalence varied from 6.5% in Bambili through 20.4% in Bambui to 60.4% in Finge. The onchocercal serological prevalence based on IgG4 detection followed a similar trend. By contrast, blood microfilariae were absent in the area as verified by use of sensitive techniques. The community prevalence of elephantiasis varied from 1.1% in Bambili to 4.4% in Bambui and 10.4% in Finge. The correlation between the parasitological prevalence of onchocerciasis and the prevalence of lymphedema in the three villages was strong (r=0.99, p<0.05). We confirm that the elephantiasis in the area is of geochemical origin and the results suggest that it is being exacerbated by onchocercal lymphadenitis.</div></front></TEI><affiliations><list><country><li>Cameroun</li></country></list><tree><noCountry><name sortKey="Amambua, Alfred Ngwa" sort="Amambua, Alfred Ngwa" uniqKey="Amambua A" first="Alfred Ngwa" last="Amambua">Alfred Ngwa Amambua</name><name sortKey="Ambele, Melvin Anyasi" sort="Ambele, Melvin Anyasi" uniqKey="Ambele M" first="Melvin Anyasi" last="Ambele">Melvin Anyasi Ambele</name><name sortKey="Titanji, Vincent P K" sort="Titanji, Vincent P K" uniqKey="Titanji V" first="Vincent P K" last="Titanji">Vincent P K. Titanji</name></noCountry><country name="Cameroun"><noRegion><name sortKey="Cho Ngwa, Fidelis" sort="Cho Ngwa, Fidelis" uniqKey="Cho Ngwa F" first="Fidelis" last="Cho-Ngwa">Fidelis Cho-Ngwa</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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